Human CD218a/IL18R1 protein (Recombinant-Active) (C-hFc-His) (STJP011772)

SKU:
STJP011772-100
£553.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD218a/IL18R1-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: IL18R1
Gene ID: 8809
Uniprot ID: IL18R_HUMAN
Immunogen Region: Glu20-Arg329
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated. N-linked glycosyl chains contribute to ligand recognition and intra-receptor interactions required for formation of an active ternary receptor complex.
Function Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3.
Protein Name Interleukin-18 Receptor 1
Il-18r-1
Il-18r1
Cd218 Antigen-Like Family Member A
Cdw218a
Il1 Receptor-Related Protein
Il-1rrp
Il1r-Rp
Interleukin-18 Receptor Alpha
Il-18r-Alpha
Il-18ralpha
Cd Antigen Cd218a
Database Links Reactome: R-HSA-9008059
Reactome: R-HSA-9012546
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-18 Receptor 1 protein
Il-18r-1 protein
Il-18r1 protein
Cd218 Antigen-Like Family Member A protein
Cdw218a protein
Il1 Receptor-Related Protein protein
Il-1rrp protein
Il1r-Rp protein
Interleukin-18 Receptor Alpha protein
Il-18r-Alpha protein
Il-18ralpha protein
Cd Antigen Cd218a protein
IL18R1 protein
IL1RRP protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP005332 Human CD218a/IL18R1 protein (Recombinant) (N-His) (STJP005332) E. coli
STJP007094 Human CD218a/IL18R1 protein (Recombinant) (C-Fc) (STJP007094) Mammalian Cells
STJP000873 Human IL-18R1/CD218a protein (Recombinant) (C-hFc&His) (STJP000873) HEK293 cells
STJP009150 Mouse CD218a/IL18R1 protein (Recombinant) (N-His) (STJP009150) E. coli
STJP011922 Human CD72 protein (Recombinant-Active) (C-hFc-His) (STJP011922) Mammalian Cells

Related Products

!