Human CD200R1/OX2R protein (Recombinant) (C-Fc) (STJP013536)

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STJP013536-100
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Short Description :Recombinant-Human CD200R1/OX2R-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:CD200R1
Gene ID:131450
Uniprot ID:MO2R1_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ala27-Leu266
Function Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Protein Name Cell Surface Glycoprotein Cd200 Receptor 1
Cd200 Cell Surface Glycoprotein Receptor
Cell Surface Glycoprotein Ox2 Receptor 1
Database Links Reactome: R-HSA-198933
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 4: Cell Membrane
Isoform 2: Secreted
Isoform 3: Secreted
Alternative Protein Names Cell Surface Glycoprotein Cd200 Receptor 1 protein
Cd200 Cell Surface Glycoprotein Receptor protein
Cell Surface Glycoprotein Ox2 Receptor 1 protein
CD200R1 protein
CD200R protein
CRTR2 protein
MOX2R protein
OX2R protein
UNQ2522 protein
PRO6015 protein

Information sourced from Uniprot.org

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