Human CD200R1/OX2R protein (Recombinant) (C-Fc) (STJP013536)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD200R1/OX2R-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | CD200R1 |
| Gene ID | 131450 |
| Uniprot ID | MO2R1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala27-Leu266 |
Additional Info
| Function | Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200. |
| Protein Name | Cell Surface Glycoprotein Cd200 Receptor 1Cd200 Cell Surface Glycoprotein ReceptorCell Surface Glycoprotein Ox2 Receptor 1 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 4: Cell MembraneIsoform 2: SecretedIsoform 3: Secreted |
| Alternative Protein Names | Cell Surface Glycoprotein Cd200 Receptor 1 proteinCd200 Cell Surface Glycoprotein Receptor proteinCell Surface Glycoprotein Ox2 Receptor 1 proteinCD200R1 proteinCD200R proteinCRTR2 proteinMOX2R proteinOX2R proteinUNQ2522 proteinPRO6015 protein |
Information sourced from Uniprot.org