Human CD108/SEMA7A protein (Recombinant) (C-Fc) (STJP007001)

SKU:
STJP007001
£469.50 - £2,492.50
Free Shipping
Processing The item has been added

Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD108/SEMA7A-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SEMA7A
Gene ID: 8482
Uniprot ID: SEM7A_HUMAN
Immunogen Region: His47-Ala648
Immunogen: Homo sapiens (Human)
Function Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Protein Name Semaphorin-7a
Cdw108
Jmh Blood Group Antigen
John-Milton-Hargen Human Blood Group Ag
Semaphorin-K1
Sema K1
Semaphorin-L
Sema L
Cd Antigen Cd108
Database Links Reactome: R-HSA-416700
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Extracellular Side
Detected In A Punctate Pattern On The Cell Membrane Of Basal And Supra-Basal Skin Keratinocytes
Alternative Protein Names Semaphorin-7a protein
Cdw108 protein
Jmh Blood Group Antigen protein
John-Milton-Hargen Human Blood Group Ag protein
Semaphorin-K1 protein
Sema K1 protein
Semaphorin-L protein
Sema L protein
Cd Antigen Cd108 protein
SEMA7A protein
CD108 protein
SEMAL protein

Information sourced from Uniprot.org