Recombinant Mouse Fas ligand/APTL/CD95 ligand/CD178 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at10-15 kDa.

Human CCL8/MCP-2 protein (Recombinant) (No-Tag) (STJP003000)

SKU:
STJP003000
£106.50 - £359.50
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Host: E.coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% Trehalose is added as protectant before lyophilisation.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <0.1 EU/Mu g
Gene Symbol: CCL8
Gene ID: 6355
Uniprot ID: CCL8_HUMAN
Immunogen Region: Gln24-Pro99
Immunogen: Recombinant Human CCL8/MCP-2 Protein by Pichia expression system. The target protein is expressed with sequence (Gln24-Pro99) of Human CCL8/MCP-2 (Accession #NP_005614.2) fused with No tag.
Immunogen Sequence: ASLAADTPTACCFSYTSRQI PQNFIADYFETSSQCSKPGV IFLTKRSRQVCADPSEEWVQ KYVSDLELSA
Tissue Specificity Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
Post Translational Modifications N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Function Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Protein Name C-C Motif Chemokine 8
Hc14
Monocyte Chemoattractant Protein 2
Monocyte Chemotactic Protein 2
Mcp-2
Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 8 protein
Hc14 protein
Monocyte Chemoattractant Protein 2 protein
Monocyte Chemotactic Protein 2 protein
Mcp-2 protein
Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 protein
CCL8 protein
MCP2 protein
SCYA10 protein
SCYA8 protein

Information sourced from Uniprot.org

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