Human CCL3L1/LD78-beta protein (Recombinant) (His-Tag) (STJP017053)

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STJP017053
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL3L1/LD78-beta-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Gene Symbol: CCL3L1.CCL3L3
Gene ID: 414062/6349
Uniprot ID: CL3L1_HUMAN
Immunogen Region: 26-93aa
Accession Number: NP_066286
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MSLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA
Post Translational Modifications The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4.
Function Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
Protein Name C-C Motif Chemokine 3-Like 1
G0/G1 Switch Regulatory Protein 19-2
Ld78-Beta(1-70
Pat 464.2
Small-Inducible Cytokine A3-Like 1
Tonsillar Lymphocyte Ld78 Beta Protein Cleaved Into - Ld78-Beta(3-70 - Ld78-Beta(5-70
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-6783783
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 3-Like 1 protein
G0/G1 Switch Regulatory Protein 19-2 protein
Ld78-Beta(1-70 protein
Pat 464.2 protein
Small-Inducible Cytokine A3-Like 1 protein
Tonsillar Lymphocyte Ld78 Beta Protein Cleaved Into - Ld78-Beta(3-70 - Ld78-Beta(5-70 protein
CCL3L1 protein
D17S1718 protein
G0S19-2 protein
SCYA3L1.CCL3L3 protein

Information sourced from Uniprot.org

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