Human CCL25/TECK protein (Recombinant) (His-Tag) (STJP019084)

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STJP019084
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL25/TECK-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCL25
Gene ID: 6370
Uniprot ID: CCL25_HUMAN
Immunogen Region: 24-150aa
Accession Number: NP_005615
Immunogen: Human
Immunogen Sequence: QGVFE DCCLAYHYPI GWAVLRRAWT YRIQEVSGSC NLPAAIFYLP KRHRKVCGNP KSREVQRAMK LLDARNKVFA KLHHNTQTFQ AGPHAVKKLS SGNSKLSSSK FSNPISSSKR NVSLLISANS GL
Tissue Specificity Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Function Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name C-C Motif Chemokine 25
Chemokine Teck
Small-Inducible Cytokine A25
Thymus-Expressed Chemokine
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 25 protein
Chemokine Teck protein
Small-Inducible Cytokine A25 protein
Thymus-Expressed Chemokine protein
CCL25 protein
SCYA25 protein
TECK protein

Information sourced from Uniprot.org

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