Human CCL25/TECK protein (Recombinant) (His-Tag) (STJP019084)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CCL25/TECK-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCL25 |
| Gene ID | 6370 |
| Uniprot ID | CCL25_HUMAN |
| Accession Number | NP_005615 |
| Immunogen | Human |
| Immunogen Region | 24-150aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine. |
| Function | Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Protein Name | C-C Motif Chemokine 25Chemokine TeckSmall-Inducible Cytokine A25Thymus-Expressed Chemokine |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 25 proteinChemokine Teck proteinSmall-Inducible Cytokine A25 proteinThymus-Expressed Chemokine proteinCCL25 proteinSCYA25 proteinTECK protein |
Information sourced from Uniprot.org