Recombinant Human CCL25/TECK Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 20-25 kDa.

Human CCL25/TECK protein (Recombinant) (C-His) (STJP003009)

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STJP003009
£123.50 - £274.50
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Gene Symbol: CCL25
Gene ID: 6370
Uniprot ID: CCL25_HUMAN
Immunogen Region: Gln24-Leu150
Immunogen: Recombinant Human CCL25/TECK Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln24-Leu150 ) of Human CCL25/TECK (Accession #NP_000726.1&NP_005615.2) fused with a His tag at the C-terminus.
Immunogen Sequence: ARGTNVGRECCLEYFKGAIP LRKLKTWYQTSEDCSRDAIV FVTVQGRAICSDPNNKRVKN AVKYLQSLERS
Tissue Specificity Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Function Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name C-C Motif Chemokine 25
Chemokine Teck
Small-Inducible Cytokine A25
Thymus-Expressed Chemokine
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 25 protein
Chemokine Teck protein
Small-Inducible Cytokine A25 protein
Thymus-Expressed Chemokine protein
CCL25 protein
SCYA25 protein
TECK protein

Information sourced from Uniprot.org

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