| Host: |
Yeast |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: |
CCL18 |
| Gene ID: |
6362 |
| Uniprot ID: |
CCL18_HUMAN |
| Immunogen Region: |
Ala21-Ala89 |
| Immunogen: |
Recombinant Human CCL18/PARC Protein is produced by Yeast expression system. The target protein is expressed with sequence (Ala21-Ala89) of human CCL18/PARC (Accession #NP_002979.1) fused with no tag. |
| Immunogen Sequence: |
AQVGTNKELCCLVYTSWQIP QKFIVDYSETSPQCPKPGVI LLTKRGRQICADPNKKWVQK YISDLKLNA |
| Post Translational Modifications | The Cys-30/Cys-54 disulfide bond is required for activity. |
| Function | Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. |
| Protein Name | C-C Motif Chemokine 18Alternative Macrophage Activation-Associated Cc Chemokine 1Amac-1Cc Chemokine ParcDendritic Cell Chemokine 1Dc-Ck1Macrophage Inflammatory Protein 4Mip-4Pulmonary And Activation-Regulated ChemokineSmall-Inducible Cytokine A18 Cleaved Into - Ccl18(1-68 - Ccl18(3-69 - Ccl18(4-69 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 18 proteinAlternative Macrophage Activation-Associated Cc Chemokine 1 proteinAmac-1 proteinCc Chemokine Parc proteinDendritic Cell Chemokine 1 proteinDc-Ck1 proteinMacrophage Inflammatory Protein 4 proteinMip-4 proteinPulmonary And Activation-Regulated Chemokine proteinSmall-Inducible Cytokine A18 Cleaved Into - Ccl18(1-68 - Ccl18(3-69 - Ccl18(4-69 proteinCCL18 proteinAMAC1 proteinDCCK1 proteinMIP4 proteinPARC proteinSCYA18 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
