Human CCL17/TARC protein (Recombinant) (N-GST) (STJP005776)

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STJP005776
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL17/TARC-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CCL17
Gene ID: 6361
Uniprot ID: CCL17_HUMAN
Immunogen Region: Ala24-Ser94
Immunogen: Homo sapiens (Human)
Function Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. May be important for the appropriate adaptation of microglial morphology and synaptic plasticity to acute lipopolysaccharide (LPS)-induced neuroinflammation. Plays a role in wound healing, mainly by inducing fibroblast migration into the wound.
Protein Name C-C Motif Chemokine 17
Cc Chemokine Tarc
Small-Inducible Cytokine A17
Thymus And Activation-Regulated Chemokine
Database Links Reactome: R-HSA-380108
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 17 protein
Cc Chemokine Tarc protein
Small-Inducible Cytokine A17 protein
Thymus And Activation-Regulated Chemokine protein
CCL17 protein
SCYA17 protein
TARC protein

Information sourced from Uniprot.org

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