| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CARD17P-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | Please contact us for further information. |
| Gene Symbol: | CARD17PUniprot ID=CAR17_HUMAN" |
| Immunogen Region: | Met1-Ser110 |
| Immunogen: | Homo sapiens (Human) |
| Function | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. |
| Protein Name | Putative Caspase Recruitment Domain-Containing Protein 17pCaspase-1 Inhibitor IncaInhibitory Caspase Recruitment Domain Protein |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Putative Caspase Recruitment Domain-Containing Protein 17p proteinCaspase-1 Inhibitor Inca proteinInhibitory Caspase Recruitment Domain Protein proteinCARD17P proteinCARD17 proteinINCA protein |
Information sourced from Uniprot.org