| Short Description : | Recombinant-Human CAPN3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | CAPN3 |
| Gene ID: | 825 |
| Uniprot ID: | CAN3_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ile602-Ala821 |
| Function | Calcium-regulated non-lysosomal thiol-protease. Proteolytically cleaves CTBP1 at 'His-409'. Mediates, with UTP25, the proteasome-independent degradation of p53/TP53. |
| Protein Name | Calpain-3Calcium-Activated Neutral Proteinase 3Canp 3Calpain L3Calpain P94Muscle-Specific Calcium-Activated Neutral Protease 3New Calpain 1Ncl-1 |
| Database Links | Reactome: R-HSA-1474228 |
| Cellular Localisation | CytoplasmNucleusNucleolus |
| Alternative Protein Names | Calpain-3 proteinCalcium-Activated Neutral Proteinase 3 proteinCanp 3 proteinCalpain L3 proteinCalpain P94 proteinMuscle-Specific Calcium-Activated Neutral Protease 3 proteinNew Calpain 1 proteinNcl-1 proteinCAPN3 proteinCANP3 proteinCANPL3 proteinNCL1 protein |
Information sourced from Uniprot.org