Human CAMLG protein (Recombinant) (His-Tag) (STJP018331)

SKU:
STJP018331
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CAMLG-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAMLG
Gene ID: 819
Uniprot ID: CAMLG_HUMAN
Immunogen Region: 1-189aa
Accession Number: NP_001736.1
Immunogen: Human
Immunogen Sequence: MESMAVA TDGGERPGVP AGSGLSASQR RAELRRRKLL MNSEQRINRI MGFHRPGSGA EEESQTKSKQ QDSDKLNSLS VPSVSKRVVL GDSVSTGTTD QQGGVAEVKG TQLGDKLDSF IKPPECSSDV NLELRQRNRG DLTADSVQRG SRHGLEQYLS RFEEAMKLRK QLISEKPSQE DGNTTEEFDS FR
Tissue Specificity Ubiquitous. Highest levels in brain, testis and ovary.
Function Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.
Protein Name Guided Entry Of Tail-Anchored Proteins Factor Camlg
Calcium Signal-Modulating Cyclophilin Ligand
Database Links Reactome: R-HSA-9609523
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Guided Entry Of Tail-Anchored Proteins Factor Camlg protein
Calcium Signal-Modulating Cyclophilin Ligand protein
CAMLG protein
CAML protein
GET2 protein

Information sourced from Uniprot.org