Human CACNA1D protein (Recombinant) (N-His) (STJP005136)

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STJP005136
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Short Description :Recombinant-Human CACNA1D-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:CACNA1D
Gene ID:776
Uniprot ID:CAC1D_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Lys163
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. Isoform Neuronal-type: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Isoform 3: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Isoform 4: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents.
Protein Name Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1d
Calcium Channel - L Type - Alpha-1 Polypeptide - Isoform 2
Voltage-Gated Calcium Channel Subunit Alpha Cav1.3
Database Links Reactome: R-HSA-400042
Reactome: R-HSA-419037
Reactome: R-HSA-422356
Reactome: R-HSA-9662360
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1d protein
Calcium Channel - L Type - Alpha-1 Polypeptide - Isoform 2 protein
Voltage-Gated Calcium Channel Subunit Alpha Cav1.3 protein
CACNA1D protein
CACH3 protein
CACN4 protein
CACNL1A2 protein
CCHL1A2 protein

Information sourced from Uniprot.org

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