Human C4orf48 protein (Recombinant) (C-His) (STJP010143)

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STJP010143
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Short Description :Recombinant-Human C4orf48-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:NICOL1
Gene ID:401115
Uniprot ID:NICOL_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Glu35-His95
Function mRNA-binding protein which interacts with a range of target mRNAs including SERPINE1, ACTA2, CCN2 and COL4A1 and may promote extracellular matrix production. Binds to the 3'-UTR of SERPINE1 mRNA and stabilizes the mRNA, possibly by competing for binding with SERBP1 and preventing SERBP1-mediated mRNA degradation. Also binds to the 3'-UTR of ACTA2. Testis-derived lumicrine factor that triggers epididymal differentiation and sperm maturation.
Protein Name Nell2-Interacting Cell Ontogeny Regulator 1
Nell2-Interacting Cofactor For Lumicrine Signaling
Nicol
Database Links
Cellular Localisation Secreted
Cytoplasm
Perinuclear Region
Detected In The Perinuclear Region Of Fibroblasts
Alternative Protein Names Nell2-Interacting Cell Ontogeny Regulator 1 protein
Nell2-Interacting Cofactor For Lumicrine Signaling protein
Nicol protein
NICOL1 protein
C4orf48 protein

Information sourced from Uniprot.org

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