| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human C1QC-N-6His & N-hFc protein was developed from hek293 cells and has a target region of N-6His & N-hFc. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
C1QC |
| Gene ID: |
714 |
| Uniprot ID: |
C1QC_HUMAN |
| Immunogen Region: |
Asn29-Asp245 |
| Immunogen: |
Recombinant HumanC1QC Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asn29-Asp245) of human ENPP-1 (Accession #P02747) fused with 6×His and hFc tag at the N-terminus. |
| Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
| Protein Name | Complement C1q Subcomponent Subunit C |
| Database Links | Reactome: R-HSA-166663Reactome: R-HSA-173623Reactome: R-HSA-977606 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Complement C1q Subcomponent Subunit C proteinC1QC proteinC1QG protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
