Function | Anti-proliferative protein.the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth. |
Protein Name | Protein Btg2Btg Family Member 2Ngf-Inducible Anti-Proliferative Protein Pc3 |
Database Links | Reactome: R-HSA-6804115 |
Alternative Protein Names | Protein Btg2 proteinBtg Family Member 2 proteinNgf-Inducible Anti-Proliferative Protein Pc3 proteinBTG2 proteinPC3 protein |
Information sourced from Uniprot.org