SDS-PAGE gel of recombinant human BPNT1 protein under reducing conditions stained with Coomassie blue

Human BPNT1 protein (Recombinant) (His-Tag) (STJP017021)

SKU:
STJP017021
£134.50 - £738.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Recombinant-Human BPNT1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 5mM DTT, 0.1M NaCl.
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:BPNT1
Gene ID:10380
Uniprot ID:BPNT1_HUMAN
Accession Number:NP_006076
Immunogen:Human
Immunogen Region:1-308aa
Immunogen Sequence:MASS NTVLMRLVAS AYSIAQKAGM IVRRVIAEGD LGIVEKTCAT DLQTKADRLA QMSICSSLAR KFPKLTIIGE EDLPSEEVDQ ELIEDSQWEE ILKQPCPSQY SAIKEEDLVV WVDPLDGTKE YTEGLLDNVT VLIGIAYEGK AIAGVINQPY YNYEAGPDAV LGRTIWGVLG LGAFGFQLKE VPAGKH
Tissue Specificity Highly expressed in kidney, liver, pancreas and heart. Detected at lower levels in brain, placenta, lung and skeletal muscle.
Function Phosphatase that converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP and inositol 1,4-bisphosphate (Ins(1,4)P2) to inositol 4-phosphate. Is also able to hydrolyze adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Probably prevents the toxic accumulation of PAP, a compound which inhibits a variety of proteins, including PAPS-utilizing enzymes such as sulfotransferases, and RNA processing enzymes. Could also play a role in inositol recycling and phosphoinositide metabolism. Is not active on 3'-AMP, inositol-1-phosphate and inositol-1,4,5-triphosphate.
Protein Name 3'(2' -5'-Bisphosphate Nucleotidase 1
3'-Phosphoadenosine 5'-Phosphate Phosphatase
Pap Phosphatase
Bisphosphate 3'-Nucleotidase 1
Bpntase 1
Hspip
Inositol-Polyphosphate 1-Phosphatase
Database Links Reactome: R-HSA-156584
Cellular Localisation
Alternative Protein Names 3'(2' -5'-Bisphosphate Nucleotidase 1 protein
3'-Phosphoadenosine 5'-Phosphate Phosphatase protein
Pap Phosphatase protein
Bisphosphate 3'-Nucleotidase 1 protein
Bpntase 1 protein
Hspip protein
Inositol-Polyphosphate 1-Phosphatase protein
BPNT1 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP010801 Human BPNT1 protein (Recombinant) (N-His) (STJP010801) E.coli ELISA/Immunogen/SDS-PAGE/WB
STJP019690 Human IRF2 protein (Recombinant) (His-Tag) (STJP019690) E.coli SDS-PAGE
STJP017768 Human CSTF1 protein (Recombinant) (His-Tag) (STJP017768) E.coli SDS-PAGE/Denatured
STJP017869 Human RNF4 protein (Recombinant) (His-Tag) (STJP017869) E.coli SDS-PAGE
STJP017870 Human NDUFA5 protein (Recombinant) (His-Tag) (STJP017870) E.coli SDS-PAGE

Related Products

!