Human BPGM protein (Recombinant) (C-His) (STJP014377)

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STJP014377-100
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Host: E.coli
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human BPGM-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 1mM DTT, pH 8.0.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: BPGM
Gene ID: 669
Uniprot ID: PMGE_HUMAN
Immunogen Region: Ser2-Lys259
Immunogen: Homo sapiens (Human)
Post Translational Modifications Glycation of Lys-159 in diabetic patients inactivates the enzyme.
Function Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase activity.
Protein Name Bisphosphoglycerate Mutase
Bpgm
2 -3-Bisphosphoglycerate Mutase - Erythrocyte
2 -3-Bisphosphoglycerate Synthase
2 -3-Diphosphoglycerate Mutase
Dpgm
Bpg-Dependent Pgam
Database Links Reactome: R-HSA-70171
Cellular Localisation
Alternative Protein Names Bisphosphoglycerate Mutase protein
Bpgm protein
2 -3-Bisphosphoglycerate Mutase - Erythrocyte protein
2 -3-Bisphosphoglycerate Synthase protein
2 -3-Diphosphoglycerate Mutase protein
Dpgm protein
Bpg-Dependent Pgam protein
BPGM protein

Information sourced from Uniprot.org

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