Human Bcl-2 related A1 protein (Recombinant) (His-Tag) (STJP017653)

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STJP017653
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Bcl-2 related A1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol
Concentration: 0.5 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: BCL2A1
Gene ID: 597
Uniprot ID: B2LA1_HUMAN
Immunogen Region: 1-152aa
Accession Number: CAG46760
Immunogen: Human
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMTDCEF GYIYRLAQDY LQYVLQIPQP GSGPSKTSRV LQKVAFSVQK EVEKNLKSCL DNVNVVSVDT ARTLFNQVME KEFEDDIINW GRIVTIFAFE GILIKKLLRQ QIAPDVDTYK EISYFVAEFI MNNTGEWIRQ NGGWENGFVK KFEPKS
Tissue Specificity Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
Function Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection. Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11.
Protein Name Bcl-2-Related Protein A1
Bcl-2-Like Protein 5
Bcl2-L-5
Hemopoietic-Specific Early Response Protein
Protein Bfl-1
Protein Grs
Database Links Reactome: R-HSA-9725371
Reactome: R-HSA-9824594
Cellular Localisation Cytoplasm
Alternative Protein Names Bcl-2-Related Protein A1 protein
Bcl-2-Like Protein 5 protein
Bcl2-L-5 protein
Hemopoietic-Specific Early Response Protein protein
Protein Bfl-1 protein
Protein Grs protein
BCL2A1 protein
BCL2L5 protein
BFL1 protein
GRS protein
HBPA1 protein

Information sourced from Uniprot.org

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