Human BAAT protein (Recombinant) (N-His) (STJP015326)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human BAAT-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | BAAT |
| Gene ID | 570 |
| Uniprot ID | BAAT_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Leu418 |
Additional Info
| Function | Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-acyl amidates with glycine and taurine. Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs. |
| Protein Name | Bile Acid-Coa -Amino Acid N-AcyltransferaseBacatBatBile Acid-Coa ThioesteraseCholoyl-Coa HydrolaseGlycine N-CholoyltransferaseLong-Chain Fatty-Acyl-Coa Hydrolase |
| Database Links | Reactome: R-HSA-159418Reactome: R-HSA-193368Reactome: R-HSA-9033241 |
| Cellular Localisation | CytoplasmCytosolPeroxisome |
| Alternative Protein Names | Bile Acid-Coa -Amino Acid N-Acyltransferase proteinBacat proteinBat proteinBile Acid-Coa Thioesterase proteinCholoyl-Coa Hydrolase proteinGlycine N-Choloyltransferase proteinLong-Chain Fatty-Acyl-Coa Hydrolase proteinBAAT protein |
Information sourced from Uniprot.org