Human ATP6V1G1 protein (Recombinant) (N-His) (STJP008331)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ATP6V1G1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ATP6V1G1 |
| Gene ID | 9550 |
| Uniprot ID | VATG1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Gly118 |
Additional Info
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. |
| Protein Name | V-Type Proton Atpase Subunit G 1V-Atpase Subunit G 1V-Atpase 13 Kda Subunit 1Vacuolar Proton Pump Subunit G 1Vacuolar Proton Pump Subunit M16 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712Reactome: R-HSA-9857377 |
| Cellular Localisation | Apical Cell Membrane |
| Alternative Protein Names | V-Type Proton Atpase Subunit G 1 proteinV-Atpase Subunit G 1 proteinV-Atpase 13 Kda Subunit 1 proteinVacuolar Proton Pump Subunit G 1 proteinVacuolar Proton Pump Subunit M16 proteinATP6V1G1 proteinATP6G proteinATP6G1 proteinATP6J protein |
Information sourced from Uniprot.org