Human ATF1 protein (Recombinant) (N-His) (STJP004230)

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STJP004230
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ATF1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ATF1
Gene ID: 466
Uniprot ID: ATF1_HUMAN
Immunogen Region: Asp3-Gln213
Immunogen: Homo sapiens (Human)
Function This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTACAG-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Protein Name Cyclic Amp-Dependent Transcription Factor Atf-1
Camp-Dependent Transcription Factor Atf-1
Activating Transcription Factor 1
Protein Treb36
Database Links Reactome: R-HSA-199920
Reactome: R-HSA-9031628
Cellular Localisation Nucleus
Alternative Protein Names Cyclic Amp-Dependent Transcription Factor Atf-1 protein
Camp-Dependent Transcription Factor Atf-1 protein
Activating Transcription Factor 1 protein
Protein Treb36 protein
ATF1 protein

Information sourced from Uniprot.org

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