Human APRIL/TNFSF13 protein (Recombinant) (T7-Tag) (STJP018701)

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STJP018701
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Host: E.coli
Applications: SDS-PAGE/Denatured
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human APRIL/TNFSF13-T7-Tag protein was developed from e.coli and has a target region of T7-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M Urea
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFSF13
Gene ID: 8741
Uniprot ID: TNF13_HUMAN
Immunogen Region: 105-247aa
Accession Number: NP_742085
Immunogen: Human
Immunogen Sequence: AVLT QKQKKQHSVL HLVPINATSK DDSDVTEVMW QPALRRGRGL QAQGYGVRIQ DAGVYLLYSQ VLFQDVTFTM GQVVSREGQG RQETLFRCIR SMPSHPDRAY NSCYSAGVFH LHQGDILSVI IPRARAKLNL SPHGTFLGL
Tissue Specificity Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
Post Translational Modifications The precursor is cleaved by furin.
Function Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Protein Name Tumor Necrosis Factor Ligand Superfamily Member 13
A Proliferation-Inducing Ligand
April
Tnf- And Apol-Related Leukocyte Expressed Ligand 2
Tall-2
Tnf-Related Death Ligand 1
Trdl-1
Cd Antigen Cd256
Database Links Reactome: R-HSA-450520
Reactome: R-HSA-5669034
Cellular Localisation Secreted
Alternative Protein Names Tumor Necrosis Factor Ligand Superfamily Member 13 protein
A Proliferation-Inducing Ligand protein
April protein
Tnf- And Apol-Related Leukocyte Expressed Ligand 2 protein
Tall-2 protein
Tnf-Related Death Ligand 1 protein
Trdl-1 protein
Cd Antigen Cd256 protein
TNFSF13 protein
APRIL protein
TALL2 protein
ZTNF2 protein
UNQ383 protein
PRO715 protein

Information sourced from Uniprot.org

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