| Short Description : | Recombinant-Active-Human APOH-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. When recombinant human ApoH is Immobilised at 2 Mu g/mL, 100 µL/well, the concentration of recombinant human LDL R that produces 50% of the optimal binding response is found to be approximately 0 |
| Gene Symbol: | APOH |
| Gene ID: | 350 |
| Uniprot ID: | APOH_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Gly20-Cys345 |
| Post Translational Modifications | N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. |
| Function | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. |
| Protein Name | Beta-2-Glycoprotein 1Apc InhibitorActivated Protein C-Binding ProteinAnticardiolipin CofactorApolipoprotein HApo-HBeta-2-Glycoprotein IB2gpiBeta(2gpi |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Beta-2-Glycoprotein 1 proteinApc Inhibitor proteinActivated Protein C-Binding Protein proteinAnticardiolipin Cofactor proteinApolipoprotein H proteinApo-H proteinBeta-2-Glycoprotein I proteinB2gpi proteinBeta(2gpi proteinAPOH proteinB2G1 protein |
Information sourced from Uniprot.org
