| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human APCS/SAP-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | APCS |
| Gene ID: | 325 |
| Uniprot ID: | SAMP_HUMAN |
| Immunogen Region: | His20-Val223 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | N-glycosylated with a complex biantennary oligosaccharide chain with a sialic acid at the end (disialo-SAP). Monosialo-SAP as well as asioalo-SAP are also detected. |
| Function | Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. |
| Protein Name | Serum Amyloid P-ComponentSap9.5s Alpha-1-Glycoprotein Cleaved Into - Serum Amyloid P-Component(1-203 |
| Database Links | Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Serum Amyloid P-Component proteinSap protein9.5s Alpha-1-Glycoprotein Cleaved Into - Serum Amyloid P-Component(1-203 proteinAPCS proteinPTX2 protein |
Information sourced from Uniprot.org