SDS-PAGE gel of recombinant human ANKRD1 protein 3µg under reducing conditions Coomassie blue stain

Human ANKRD1 protein (Recombinant) (His-Tag) (STJP017827)

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STJP017827
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Short Description :Recombinant-Human ANKRD1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.5) containing 0.2M NaCl, 50% Glycerol, 5mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:ANKRD1
Gene ID:27063
Uniprot ID:ANKR1_HUMAN
Accession Number:NP_055206
Immunogen:Human
Immunogen Region:1-319aa
Immunogen Sequence:MVLKVE ELVTGKKNGN GEAGEFLPED FRDGEYEAAV TLEKQEDLKT LLAHPVTLGE QQWKSEKQRE AELKKKKLEQ RSKLENLEDL EIIIQLKKRK KYRKTKVPVV KEPEPEIITE PVDVPTFLKA ALENKLPVVE KFLSDKNNPD VCDEYKRTAL HRACLEGHLA IVEKLMEAGA QIEFRDMLES TAIHWASRGG NLDVLK
Tissue Specificity Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells.
Function May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.
Protein Name Ankyrin Repeat Domain-Containing Protein 1
Cardiac Ankyrin Repeat Protein
Cytokine-Inducible Gene C-193 Protein
Cytokine-Inducible Nuclear Protein
Database Links Reactome: R-HSA-1989781
Cellular Localisation Nucleus
Alternative Protein Names Ankyrin Repeat Domain-Containing Protein 1 protein
Cardiac Ankyrin Repeat Protein protein
Cytokine-Inducible Gene C-193 Protein protein
Cytokine-Inducible Nuclear Protein protein
ANKRD1 protein
C193 protein
CARP protein
HA1A2 protein

Information sourced from Uniprot.org

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