Human Angiopoietin-like 7/ANGPTL7 protein (Recombinant) (hIgG-Tag) (STJP019508)

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STJP019508
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Host: HEK293 Cells
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human Angiopoietin-like 7/ANGPTL7-hIgG-Tag protein was developed from hek293 cells and has a target region of hIgG-Tag. For use in research applications.
Formulation: Liquid In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Gene Symbol: ANGPTL7
Gene ID: 10218
Uniprot ID: ANGL7_HUMAN
Immunogen Region: 27-346aa
Accession Number: NP_066969.1
Immunogen: Human
Immunogen Sequence: QKLSKHKTPA QPQLKAANCC EEVKELKAQV ANLSSLLSEL NKKQERDWVS VVMQVMELES NSKRMESRLT DAESKYSEMN NQIDIMQLQA AQTVTQTSAD AIYDCSSLYQ KNYRISGVYK LPPDDFLGSP ELEVFCDMET SGGGWTIIQR RKSGLVSFYR DWKQYKQGFG SIRGDFWLGN EHIHRLSRQP TRLRVEMEDW EGNLRYAEYS HFVLGNELNS YRLFLGNY
Tissue Specificity Highly expressed in the cornea (at protein level). Expression is restricted to the stromal layer. Also detected at the junction between the corneal stromal layer and the conjuctiva. Not detected in the sclera.
Function Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure. Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency.
Protein Name Angiopoietin-Related Protein 7
Angiopoietin-Like Factor
Angiopoietin-Like Protein 7
Cornea-Derived Transcript 6 Protein
Database Links
Cellular Localisation Secreted
Alternative Protein Names Angiopoietin-Related Protein 7 protein
Angiopoietin-Like Factor protein
Angiopoietin-Like Protein 7 protein
Cornea-Derived Transcript 6 Protein protein
ANGPTL7 protein
CDT6 protein
UNQ313 protein
PRO356 protein

Information sourced from Uniprot.org

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