Human Angiopoietin-4/ANG-4/ANGPT4 (23-503) protein (Recombinant) (N-6His) (STJP003095)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Angiopoietin-4/ANG-4/ANGPT4 (23-503) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln23-Ile503) of human ANG-4/ANGPT4 (Accession #NP_057069.1) fused with and a 6×His tag at th
General Information
| Short Description | Recombinant-Human Angiopoietin-4/ANG-4/ANGPT4 (23-503)-N-6His protein was developed in hek293 cells using the region Gln23-Ile503. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | <0.1 EU/Mu g |
Target Information
| Gene Symbol | ANGPT4 |
| Gene ID | 51378 |
| Uniprot ID | ANGP4_HUMAN |
| Immunogen | Recombinant Human Angiopoietin-4/ANG-4/ANGPT4 (23-503) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln23-Ile503) of human ANG-4/ANGPT4 (Accession #NP_057069.1) fused with and a 6×His tag at th |
| Immunogen Region | Gln23-Ile503 |
| Immunogen Sequence | RGQRGKNRGCVLTAIHLNVT DLGLGYETKEELIFRYCSGS CDAAETTYDKILKNLSRNRR LVSDKVGQACCRPIAFDDDL SFLDDNLVYHILRKHSAKRC GCI |
Additional Info
| Tissue Specificity | Highly expressed in the lung with much lower levels found in other tissues. |
| Function | Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. |
| Protein Name | Angiopoietin-4Ang-4Angiopoietin-3Ang-3 |
| Database Links | Reactome: R-HSA-210993 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Angiopoietin-4 proteinAng-4 proteinAngiopoietin-3 proteinAng-3 proteinANGPT4 proteinANG3 proteinANG4 protein |
Information sourced from Uniprot.org