Human ANAPC13 protein (Recombinant) (T7-Tag) (STJP017532)

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STJP017532
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ANAPC13-T7-Tag protein was developed from e.coli and has a target region of T7-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 1mM DTT, 0.1M NaCl
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: ANAPC13
Gene ID: 25847
Uniprot ID: APC13_HUMAN
Immunogen Region: 1-74aa
Accession Number: NP_056206
Immunogen: Human
Immunogen Sequence: MASMTGGQQM GRGSHMDSEV QRDGRILDLI DDAWREDKLP YEDVAIPLNE LPEPEQDNGG TTESVKEQEM KWTDLALQYL HENVPPIGN
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.
Protein Name Anaphase-Promoting Complex Subunit 13
Apc13
Cyclosome Subunit 13
Database Links Reactome: R-HSA-983168
Cellular Localisation Nucleus
Alternative Protein Names Anaphase-Promoting Complex Subunit 13 protein
Apc13 protein
Cyclosome Subunit 13 protein
ANAPC13 protein

Information sourced from Uniprot.org

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