| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human AMSH-LP-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% Glycerol, 0.1mM PMSF |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STAMBPL1 |
| Gene ID: | 57559 |
| Uniprot ID: | STALP_HUMAN |
| Immunogen Region: | 1-436aa |
| Accession Number: | NP_065850 |
| Immunogen: | Human |
| Immunogen Sequence: |
| Tissue Specificity | Ubiquitously expressed. |
| Function | Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex. Does not cleave 'Lys-48'-linked polyubiquitin chains. |
| Protein Name | Amsh-Like ProteaseAmsh-LpStam-Binding Protein-Like 1 |
| Database Links | Reactome: R-HSA-5689901 |
| Cellular Localisation | |
| Alternative Protein Names | Amsh-Like Protease proteinAmsh-Lp proteinStam-Binding Protein-Like 1 proteinSTAMBPL1 proteinAMSHLP proteinKIAA1373 protein |
Information sourced from Uniprot.org