Name: Human ACVR1C protein (Recombinant) (N-His) (STJP005721)
SKU: STJP005721
Availability: InStock

Human ACVR1C protein (Recombinant) (N-His) (STJP005721)

SKU:

STJP005721

£222.50 - £1,177.50

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Host:	E.coli
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human ACVR1C-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consists of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B, activin E and NODAL. Upon NODAL binding, activation results in increased apoptosis and reduced proliferation through suppression of AKT signaling and the activation of Smad2-dependent signaling pathway in pancreatic beta-cells, trophoblasts, epithelial or neuronal cells. Acts as a positive regulator for macrophage activation partially through down-regulation of PPARG expression.
Protein Name	Activin Receptor Type-1c Activin Receptor Type Ic Actr-Ic Activin Receptor-Like Kinase 7 Alk-7
Database Links	Reactome: R-HSA-1181150 Reactome: R-HSA-1433617 Reactome: R-HSA-1502540
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Activin Receptor Type-1c protein Activin Receptor Type Ic protein Actr-Ic protein Activin Receptor-Like Kinase 7 protein Alk-7 protein ACVR1C protein ALK7 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP001023	Human ALK-7/ACVR1C protein (Recombinant) (C-hFc&His) (STJP001023)	HEK293 cells
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP006145	Human TJP2 protein (Recombinant) (N-His) (STJP006145)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP009675	Human NEIL3 protein (Recombinant) (N-His) (STJP009675)	E.coli	ELISA/Immunogen/SDS-PAGE/WB

Human ACVR1C protein (Recombinant) (N-His) (STJP005721)

General Information