| Tissue Specificity | Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue. |
| Function | Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway. |
| Protein Name | Acyl-Coenzyme A Thioesterase 11Acyl-Coa Thioesterase 11Acyl-Coa Thioester Hydrolase 11Adipose-Associated ThioesteraseBrown Fat-Inducible ThioesteraseBfitPalmitoyl-Coenzyme A Thioesterase |
| Database Links | Reactome: R-HSA-77289 |
| Cellular Localisation | Mitochondrion MatrixCytoplasm |
| Alternative Protein Names | Acyl-Coenzyme A Thioesterase 11 proteinAcyl-Coa Thioesterase 11 proteinAcyl-Coa Thioester Hydrolase 11 proteinAdipose-Associated Thioesterase proteinBrown Fat-Inducible Thioesterase proteinBfit proteinPalmitoyl-Coenzyme A Thioesterase proteinACOT11 proteinBFIT proteinKIAA0707 proteinTHEA protein |
Information sourced from Uniprot.org