Human ACAT1 protein (Recombinant) (N-His) (STJP004403)

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STJP004403
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Short Description :Recombinant-Human ACAT1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:ACAT1
Gene ID:38
Uniprot ID:THIL_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ala111-Leu427
Function This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism.
Protein Name Acetyl-Coa Acetyltransferase - Mitochondrial
Acetoacetyl-Coa Thiolase
T2
Database Links Reactome: R-HSA-70895
Reactome: R-HSA-77108
Reactome: R-HSA-77111
Reactome: R-HSA-9837999
Reactome: R-HSA-9854311
Reactome: R-HSA-9915355
Cellular Localisation Mitochondrion
Alternative Protein Names Acetyl-Coa Acetyltransferase - Mitochondrial protein
Acetoacetyl-Coa Thiolase protein
T2 protein
ACAT1 protein
ACAT protein
MAT protein

Information sourced from Uniprot.org