Human ACAT1 protein (Recombinant) (N-His) (STJP004403)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ACAT1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ACAT1 |
| Gene ID | 38 |
| Uniprot ID | THIL_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala111-Leu427 |
Additional Info
| Function | This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. |
| Protein Name | Acetyl-Coa Acetyltransferase - MitochondrialAcetoacetyl-Coa ThiolaseT2 |
| Database Links | Reactome: R-HSA-70895Reactome: R-HSA-77108Reactome: R-HSA-77111Reactome: R-HSA-9837999Reactome: R-HSA-9854311Reactome: R-HSA-9915355 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Acetyl-Coa Acetyltransferase - Mitochondrial proteinAcetoacetyl-Coa Thiolase proteinT2 proteinACAT1 proteinACAT proteinMAT protein |
Information sourced from Uniprot.org