Human ABCF1 protein (Recombinant) (N-His) (STJP005716)

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STJP005716
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ABCF1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ABCF1
Gene ID: 23
Uniprot ID: ABCF1_HUMAN
Immunogen Region: Leu625-Glu845
Immunogen: Homo sapiens (Human)
Post Translational Modifications Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes.
Function Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
Protein Name Atp-Binding Cassette Sub-Family F Member 1
Atp-Binding Cassette 50
Tnf-Alpha-Stimulated Abc Protein
Database Links Reactome: R-HSA-382556
Cellular Localisation Isoform 2: Cytoplasm
Nucleus
Nucleoplasm
Nucleus Envelope
Alternative Protein Names Atp-Binding Cassette Sub-Family F Member 1 protein
Atp-Binding Cassette 50 protein
Tnf-Alpha-Stimulated Abc Protein protein
ABCF1 protein
ABC50 protein

Information sourced from Uniprot.org

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