Host: |
HEK293 |
Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human 4-1BB/TNFRSF9-C-hFc-Avi protein was developed from hek293 and has a target region of C-hFc-Avi. For use in research applications. |
Conjugation: |
Biotin |
Formulation: |
Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
Dilution Range: |
Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
Storage Instruction: |
The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Gene Symbol: |
TNFRSF9 |
Gene ID: |
3604 |
Uniprot ID: |
TNR9_HUMAN |
Immunogen Region: |
Leu24-Gln186 |
Immunogen: |
DNA sequence encoding Human 4-1BB/TNFRSF9 including a C-hFc-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
Function | Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 94-1bb Ligand ReceptorCdw137T-Cell Antigen 4-1bb HomologT-Cell Antigen IlaCd Antigen Cd137 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 9 protein4-1bb Ligand Receptor proteinCdw137 proteinT-Cell Antigen 4-1bb Homolog proteinT-Cell Antigen Ila proteinCd Antigen Cd137 proteinTNFRSF9 proteinCD137 proteinILA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance