Human 14-3-3 eta protein (Recombinant) (His-Tag) (STJP019810)

SKU:
STJP019810
£134.50 - £738.50
Processing The item has been added

Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human 14-3-3 eta-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) , 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: YWHAH
Gene ID: 7533
Uniprot ID: 1433F_HUMAN
Immunogen Region: 1-246aa
Accession Number: NP_003396
Immunogen: Human
Immunogen Sequence: MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIA
Tissue Specificity Expressed mainly in the brain and present in other tissues albeit at lower levels.
Post Translational Modifications Phosphorylated on Ser-59 by protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion.
Function Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Protein Name 14-3-3 Protein Eta
Protein As1
Database Links Reactome: R-HSA-111447
Reactome: R-HSA-1445148
Reactome: R-HSA-5625740
Reactome: R-HSA-5628897
Reactome: R-HSA-75035
Reactome: R-HSA-9735871
Reactome: R-HSA-9755779
Reactome: R-HSA-9856649
Cellular Localisation
Alternative Protein Names 14-3-3 Protein Eta protein
Protein As1 protein
YWHAH protein
YWHA1 protein

Information sourced from Uniprot.org