| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
HAND2 Positive Control for STJ501310 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Hand2 |
| Gene ID: |
64637 |
| Uniprot ID: |
HAND2_RAT |
| Specificity: |
This is positive control is recommended for use in combination with HAND2 antibody STJ501310. |
| Function | Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. |
| Peptide Name | Heart- And Neural Crest Derivatives-Expressed Protein 2Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2Dhand |
| Cellular Localisation | Nucleus |
| Alternative Peptide Names | Heart- And Neural Crest Derivatives-Expressed Protein 2 proteinDeciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2 proteinDhand proteinHand2 proteinDhand protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
