ImmunogenSynthetic peptide corresponding to C terminal amino acids 490-500 of Human Glucose Transporter 5 GLUT5. A cysteine residue was included at the N-terminus of the peptide to accommodate KLH conjugation. Sequence: ELKEPPVTSEQ
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Glucose transporter GLUT5 Blocking Peptide is synthetically produced from the 490-500 sequence and is suitable for use in western blot applications.
Applications
Immunodepletion/Immunocompetition
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Formulation
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction
Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Synthetic peptide corresponding to C terminal amino acids 490-500 of Human Glucose Transporter 5 GLUT5. A cysteine residue was included at the N-terminus of the peptide to accommodate KLH conjugation. Sequence: ELKEPPVTSEQ
Immunogen Region
490-500
Additional Info
Tissue Specificity
Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.
Function
Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of 2-deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.
Peptide Name
Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5Fructose TransporterGlucose Transporter Type 5 - Small IntestineGlut-5
Apical Cell MembraneMulti-Pass Membrane ProteinCell MembraneSarcolemmaLocalized On The Apical Membrane Of Jejunum VilliBut Also On Lateral Plasma Membranes Of The VilliTransport To The Cell Membrane Is Dependent On Rab11a
Alternative Peptide Names
Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5 proteinFructose Transporter proteinGlucose Transporter Type 5 - Small Intestine proteinGlut-5 proteinSLC2A5 proteinGLUT5 protein
