GGCX Positive Control for STJ501153 peptide (STJ504180)

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STJ504180-5
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Covered by St John's Laboratory Guarantee

Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : GGCX Positive Control for STJ501153 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: GGCX
Gene ID: 2677
Uniprot ID: VKGC_HUMAN
Specificity: This is positive control is recommended for use in combination with GGCX antibody STJ501153.
Function Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. Catalyzes gamma-carboxylation of various proteins, such as blood coagulation factors (F2, F7, F9 and F10), osteocalcin (BGLAP) or matrix Gla protein (MGP).
Peptide Name Vitamin K-Dependent Gamma-Carboxylase
Gamma-Glutamyl Carboxylase
Peptidyl-Glutamate 4-Carboxylase
Vitamin K Gamma Glutamyl Carboxylase
Database Links Reactome: R-HSA-159740
Reactome: R-HSA-9673240
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Vitamin K-Dependent Gamma-Carboxylase protein
Gamma-Glutamyl Carboxylase protein
Peptidyl-Glutamate 4-Carboxylase protein
Vitamin K Gamma Glutamyl Carboxylase protein
GGCX protein
GC protein

Information sourced from Uniprot.org

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