GGCX Positive Control for STJ501153 peptide (STJ504180)
SPECIFICATIONS
General Information
| Short Description | GGCX Positive Control for STJ501153 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | GGCX |
| Gene ID | 2677 |
| Uniprot ID | VKGC_HUMAN |
| Specificity | This is positive control is recommended for use in combination with GGCX antibody STJ501153. |
Additional Info
| Function | Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. Catalyzes gamma-carboxylation of various proteins, such as blood coagulation factors (F2, F7, F9 and F10), osteocalcin (BGLAP) or matrix Gla protein (MGP). |
| Peptide Name | Vitamin K-Dependent Gamma-CarboxylaseGamma-Glutamyl CarboxylasePeptidyl-Glutamate 4-CarboxylaseVitamin K Gamma Glutamyl Carboxylase |
| Database Links | Reactome: R-HSA-159740Reactome: R-HSA-9673240 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Vitamin K-Dependent Gamma-Carboxylase proteinGamma-Glutamyl Carboxylase proteinPeptidyl-Glutamate 4-Carboxylase proteinVitamin K Gamma Glutamyl Carboxylase proteinGGCX proteinGC protein |
Information sourced from Uniprot.org