| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
GAD65 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Post Translational Modifications | Phosphorylated.which does not affect kinetic parameters or subcellular location. Palmitoylated.which is required for presynaptic clustering. |
| Function | Catalyzes the production of GABA. |
| Peptide Name | Glutamate Decarboxylase 265 Kda Glutamic Acid DecarboxylaseGad-65Glutamate Decarboxylase 65 Kda Isoform |
| Database Links | Reactome: R-HSA-888568Reactome: R-HSA-888590Reactome: R-HSA-9022927 |
| Cellular Localisation | CytoplasmCytosolCytoplasmic VesiclePresynaptic Cell MembraneLipid-AnchorGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideAssociated To Cytoplasmic VesiclesIn NeuronsCytosolic Leaflet Of Golgi Membranes And Presynaptic Clusters |
| Alternative Peptide Names | Glutamate Decarboxylase 2 protein65 Kda Glutamic Acid Decarboxylase proteinGad-65 proteinGlutamate Decarboxylase 65 Kda Isoform proteinGAD2 proteinGAD65 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
