| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Biotin |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Immunogen Region: | Gln22-Asp117 |
| Immunogen: | Biotinylated Recombinant Cynomolgus CD3E&CD3D Protein (Primary Amine Labeling) is produced by Expi293 expression system. The target protein is expressed with sequence (Gln22-Asp117 (CD3E) &Phe22-Ala105 (CD3D) ) of Cynomolgus CD3E&CD3D fused with a hF |
| Immunogen Sequence: | QDGNEEMGSITQTPYQVSIS GTTVILTCSQHLGSEAQWQH NGKNKEDSGDRLFLPEFSEM EQSGYYVCYPRGSNPEDASH HLYLKARVCENCMEMDFKIP IEELEDRVFVNCNTSITWVE GTVGTLLSDITRLDLGKRIL DPRGIYRCNGTDIYKDKEST VQVHYRMCQSCVELDPATVA |
| Background | T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D, are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR) , TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. |
Information sourced from Uniprot.org
