Cynomolgus CD3E&CD3D (Primary Amine Labeling) protein (Recombinant) (C-hFc) {Biotin} (STJP020338)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Cynomolgus CD3E&CD3D Protein (Primary Amine Labeling) is produced by Expi293 expression system. The target protein is expressed with sequence (Gln22-Asp117 (CD3E) &Phe22-Ala105 (CD3D) ) of Cynomolgus CD3E&CD3D fused with a hF
General Information
| Short Description | Recombinant-Cynomolgus CD3E&CD3D (Primary Amine Labeling)-C-hFc protein was developed in hek293 cells using the region Gln22-Asp117. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Biotinylated Recombinant Cynomolgus CD3E&CD3D Protein (Primary Amine Labeling) is produced by Expi293 expression system. The target protein is expressed with sequence (Gln22-Asp117 (CD3E) &Phe22-Ala105 (CD3D) ) of Cynomolgus CD3E&CD3D fused with a hF |
| Immunogen Region | Gln22-Asp117 |
| Immunogen Sequence | QDGNEEMGSITQTPYQVSIS GTTVILTCSQHLGSEAQWQH NGKNKEDSGDRLFLPEFSEM EQSGYYVCYPRGSNPEDASH HLYLKARVCENCMEMDFKIP IEELEDRVFVNCNTSITWVE GTVGTLLSDITRLDLGKRIL DPRGIYRCNGTDIYKDKEST VQVHYRMCQSCVELDPATVA |
Additional Info
| Background | T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D, are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR) , TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. |
Information sourced from Uniprot.org