Cynomolgus B7-2/CD86 protein (Recombinant) (C-His) (STJP020268)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Cynomolgus B7-2/CD86 Protein is expressed from Expi293 with His tag at the C-terminal.οΌIt contains Tyr26-His240.
General Information
| Short Description | Recombinant-Cynomolgus B7-2/CD86-C-His protein was developed in hek293 cells using the region Tyr26-His240. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Recombinant Cynomolgus B7-2/CD86 Protein is expressed from Expi293 with His tag at the C-terminal.οΌIt contains Tyr26-His240. |
| Immunogen Region | Tyr26-His240 |
Additional Info
| Background | B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively. |
Information sourced from Uniprot.org