| Tissue Specificity | Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons. |
| Function | Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. |
| Peptide Name | Protein-S-Isoprenylcysteine O-MethyltransferaseIsoprenylcysteine CarboxylmethyltransferasePrenylated Protein Carboxyl MethyltransferasePpmtPrenylcysteine Carboxyl MethyltransferasePccmt |
| Database Links | Reactome: R-HSA-163841Reactome: R-HSA-9648002 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Protein-S-Isoprenylcysteine O-Methyltransferase proteinIsoprenylcysteine Carboxylmethyltransferase proteinPrenylated Protein Carboxyl Methyltransferase proteinPpmt proteinPrenylcysteine Carboxyl Methyltransferase proteinPccmt proteinICMT proteinPCCMT protein |
Information sourced from Uniprot.org