| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
CMT Blocking Peptide is synthetically produced from the 230-284 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
ICMT |
| Gene ID: |
23463 |
| Uniprot ID: |
ICMT_HUMAN |
| Immunogen Region: |
230-284 |
| Immunogen: |
Synthetic peptide taken within amino acid region 230-284 on human Protein-S-isoprenylcysteine O-methyltransferase. |
| Tissue Specificity | Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons. |
| Function | Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. |
| Peptide Name | Protein-S-Isoprenylcysteine O-MethyltransferaseIsoprenylcysteine CarboxylmethyltransferasePrenylated Protein Carboxyl MethyltransferasePpmtPrenylcysteine Carboxyl MethyltransferasePccmt |
| Database Links | Reactome: R-HSA-163841Reactome: R-HSA-9648002 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Protein-S-Isoprenylcysteine O-Methyltransferase proteinIsoprenylcysteine Carboxylmethyltransferase proteinPrenylated Protein Carboxyl Methyltransferase proteinPpmt proteinPrenylcysteine Carboxyl Methyltransferase proteinPccmt proteinICMT proteinPCCMT protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
