CMT Blocking Peptide peptide (STJ504241)

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STJ504241-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : CMT Blocking Peptide is synthetically produced from the 230-284 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ICMT
Gene ID: 23463
Uniprot ID: ICMT_HUMAN
Immunogen Region: 230-284
Immunogen: Synthetic peptide taken within amino acid region 230-284 on human Protein-S-isoprenylcysteine O-methyltransferase.
Tissue Specificity Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons.
Function Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
Peptide Name Protein-S-Isoprenylcysteine O-Methyltransferase
Isoprenylcysteine Carboxylmethyltransferase
Prenylated Protein Carboxyl Methyltransferase
Ppmt
Prenylcysteine Carboxyl Methyltransferase
Pccmt
Database Links Reactome: R-HSA-163841
Reactome: R-HSA-9648002
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Protein-S-Isoprenylcysteine O-Methyltransferase protein
Isoprenylcysteine Carboxylmethyltransferase protein
Prenylated Protein Carboxyl Methyltransferase protein
Ppmt protein
Prenylcysteine Carboxyl Methyltransferase protein
Pccmt protein
ICMT protein
PCCMT protein

Information sourced from Uniprot.org

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